Head of the Group

Prof. Dr. Hans-Peter Deigner

Biomarker and molecular diagnostics

Phone: +49 (0) 7720 307 4232
Email: dei@hs-furtwangen.de
https://www.hs-furtwangen.de/personen/profil/332-hans-peterdeigner/
Office B2.06

Current Projects

Group Members

Max Bogolte

Academic staff

Phone: +49 (0) 7720 307 4364

box@hs-furtwangen.de

Office M 2.01

Dr. Cristian Aldemar Gasca Silva

Academic staff

Phone: +49 (0) 7720 307 4347

gasi@hs-furtwangen.de

Office C 2.03

Lars Kaiser

Academic staff

Phone: +49 (0) 7720 307 4629

kal@hs-furtwangen.de

Office M2.02

Dr. Abid Ali Khan

Academic staff

Phone: +49 (0) 7720 307 4618

kaa@hs-furtwangen.de

Office C 2.03

Dr. Fungisai Matemadombo

Academic staff

Levin Nopper

Academic staff

Phone: +49 (0) 7720 307 4635

nole@hs-furtwangen.de

Office B 2.07

Isabel Quint

Academic staff

Phone: +49 (0) 7720 307 4330

qui@hs-furtwangen.de

Office B 2.04

Simone Rentschler

Academic staff

Phone: +49 (0) 7720 307 4757

ren@hs-furtwangen.de

Office B 2.04

Oliver Riester

Academic staff

Phone: +49 (0) 7720 307 4514

riol@hs-furtwangen.de

Office M 2.02

Helga Weinschrott

Academic staff

Phone: +49 (0) 7720 307 4326

weh@hs-furtwangen.de

Office B 2.04

Current Projects

FlowArray – Functional lateral flow arrays for the identification of multi-resistant pathogens

The aim of project “FlowArray” is to develop functional multiplex lateral flow microarrays (LFMAs) for point-of-care (POC) analysis of infections with multi-resistant pathogens. The microarray format allows identification of a variety of different pathogens, their resistances, and effective inhibitors on a single test strip.

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TriMaBone – Trinational research initiative: 3D printing materials for resorbable bone implants

The aim of project “TriMaBone” is to create materials and production techniques which enable the application of additive manufacturing / 3D printing of Chitosan-based materials in the medical field of bone reconstruction.

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AsphyxDx – Translation of clinical markers of neonatal oxygen deficiency into a new diagnostic tool to prevent early infant brain damage and guide individualized therapy

The aim of project “AsphyxDx” is to develop a diagnostic approach for perinatal asphyxia based on the quantification of small endogenous metabolites using nanopore-based, as well as other, rapid tests. Reliable diagnosis of perinatal asphyxia is the prerequisite for timely therapy based on cold treatment (hypothermia) to avoid irreversible late damage.

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CompanionDx Hypothermie – Joint project: Therapy-accompanying diagnosis for oxygen deficiency in newborns

The aim of project “CompanionDx” is to identify metabolic biomarkers for the differentiation between responders and non-responders of hypothermia therapy applied during the treatment of children with perinatal asphyxia. The biomarkers will be used for early prediction if an affected child will benefit from hypothermia therapy or if an alternative therapeutic strategy should be chosen.

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InfektResonator_WGM – Microresonators for point-of-care diagnostics of pathogens

The aim of the InfektResonator project is to further develop Whispering Gallery Mode (WGM) sensor technology into a rapid analysis platform for rapid diagnostic tests. The low detection limits of up to 50 fmol are to be used for the analysis of antibiotic resistance of pathogens without prior culture.

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TechPat nano – New technologies for patients – Translational platform for nanosensor-based medical diagnostics

The aim of “TechPat nano” project is the development of a therapy-accompanying, non-invasive monitoring test after kidney transplantation to enable early detection of transplant rejection. The test will function by determining the molecular marker “kynurenine” to enable immunosuppressants to be adjusted in a course-specific manner.

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The Washing Machine Microbiome Project (WMP)

During this project, the microbiome of washing machines and worn textiles, and changes due to washing processes will be investigated with a particular interest on the presence of antibiotic-resistant bacteria. Extensive metabolome analyses of microbial metabolites from relevant sample materials will be performed with mass spectrometry to determine relevant metabolic activities of the microorganisms.

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PersonaMed – Individualized strategies for medicine and medical technology

The aim of project “PersonaMed” is the development of novel materials for the treatment of cerebral aneurysms based on hydrogels. The materials are expected to provide better aneurysm filling with improved regeneration and endothelialization as well as reduced recurrence with lower risk application.

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CARBaBIO

Investigation of the possibility for the stereoselective production of carba sugar derivatives in high purity and yield, starting from simple basic chemicals. The investigation of biological properties or biological effects will be used as a basis for the selection of further target substances.

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Selected Publications

Former Members

Former Projects

MultiFlow - CoHMed MS-Tox Test

The aim of project “MS-Tox Test” is to identify metabolic biomarkers for toxicity reactions to improve cytotoxicity testing in context of biological evaluation of medical devices. Combining the standardized cytotoxicity assay (DIN EN ISO 10993 series of standards) with mass spectrometry is expected to increase the power of such assays, detect material-induced changes (and potential risks) earlier and more sensitively at the molecular level.

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